Museo Zacatecano

Museo Zacatecan, or Zacatecan Museum, is located in the city's historic center and was the headquarters of the Zacatecas Mint, which was founded in 1826. Federico Sescosse Lejeune, a Zacatecan celebrity who dedicated his life to defending and maintaining the cultural legacy of Zacatecas, founded the museum in 1995. Its collection is divided into three thematic lines: Huichol Culture and Art, an encounter with a living ancestral culture that is part of today's cultural diversity in Mexico; Popular Religious Imaginary of the Nineteenth Century, an approach to popular religious iconography that is a relic of an artistic past; and Colonial Forged Irons, notable examples of applied arts.

The primary temple of the Diocese of Zacatecas is the Zacatecas Cathedral, which is dedicated to the Virgin of the Assumption. Located in the city's historic core and is designated by UNESCO as a Cultural Heritage of Humanity. There were two temples before the current structure. The earliest was constructed in 1568 as a tiny parish of the city. In the place of the old temple, a second temple was erected, which was consecrated in 1625.